FGF-2 Polyclonal Antibody
¥680.00
SRPK1 (Phospho Thr601) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612433
- 产品信息
商品描述
靶点-Target
SRPK1
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
74kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human SRPK1 (Phospho-Thr601)
特异性
This antibody detects endogenous levels of SRPK1 (Phospho-Thr601) at Human, Mouse,Rat
基因名称
SRPK1
蛋白名称
SRPK1 (Phospho-Thr601)
别名
SRSF protein kinase 1;SFRS protein kinase 1;Serine/arginine-rich protein-specific kinase 1;SR-protein-specific kinase 1;
Organism-1
Human
基因ID-1
6732
SwissProt-1
Q96SB4
Organism-2
Mouse
基因ID-2
20815
SwissProt-2
O70551
背景
This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. Alternative splicing of this gene results in multiple transcript variants. Additional alternatively spliced transcript variants have been described for this gene, but their full length nature have not been determined.[provided by RefSeq, Jul 2010],
细胞定位
[Isoform 2]: Cytoplasm. Nucleus. Nucleus matrix. Microsome. Shuttles between the nucleus and the cytoplasm. Inhibition of the Hsp90 ATPase activity, osmotic stress and interaction with HHV-1 ICP27 protein can induce its translocation to the nucleus. KAT5/TIP60 inhibits its nuclear translocation.; [Isoform 1]: Cytoplasm. Nucleus matrix. Microsome. Mainly localized in the microsomal fraction and the cytoplasm, and to a lesser extent in the nuclear matrix.; Cytoplasm . Nucleus, nucleoplasm . Nucleus speckle . Chromosome . Preferentially localizes to the promoter of gene coding regions. .
