ILK-1 (Phospho Ser343) rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612417

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商品描述
  • 靶点-Target

    ILK

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Calculated)

    50kD

  • 推荐稀释比

    WB 1:500-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human ILK-1 (Phospho-Ser343)

  • 特异性

    This antibody detects endogenous levels of ILK-1 (Phospho-Ser343) at Human, Mouse,Rat

  • 基因名称

    ILK ILK1 ILK2

  • 蛋白名称

    ILK-1 (Phospho-Ser343)

  • 别名

    Integrin-linked protein kinase;59 kDa serine/threonine-protein kinase;ILK-1;ILK-2;p59ILK;

  • Organism-1

    Human

  • 基因ID-1

    3611

  • SwissProt-1

    Q13418

  • Organism-2

    Mouse

  • 基因ID-2

    16202

  • SwissProt-2

    O55222

  • Organism-3

    Rat

  • 基因ID-3

    170922

  • SwissProt-3

    Q99J82

  • 背景

    This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],

  • 细胞定位

    Cell junction, focal adhesion . Cell membrane; Peripheral membrane protein; Cytoplasmic side . Cell projection, lamellipodium . Cytoplasm, myofibril, sarcomere .