Connexin 43 (Phospho Ser373) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612407
- 产品信息
商品描述
靶点-Target
Connexin 43
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
43kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Connexin 43 (Phospho-Ser373)
特异性
This antibody detects endogenous levels of Connexin 43 (Phospho-Ser373) at Human, Mouse,Rat
基因名称
GJA1 GJAL
蛋白名称
Connexin 43 (Phospho-Ser373)
别名
Gap junction alpha-1 protein;Connexin-43;Cx43;Gap junction 43 kDa heart protein;
Organism-1
Human
基因ID-1
2697
SwissProt-1
P17302
Organism-2
Mouse
基因ID-2
14609
SwissProt-2
P23242
Organism-3
Rat
基因ID-3
24392
SwissProt-3
P08050
背景
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. [provided by RefSeq, May 2014],
细胞定位
Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction . Endoplasmic reticulum . Localizes at the intercalated disk (ICD) in cardiomyocytes and the proper localization at ICD is dependent on TMEM65. .





