FGF-2 Polyclonal Antibody
¥680.00
DYRK1A/B (Phospho Tyr321/273) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612387
- 产品信息
商品描述
靶点-Target
DYRK1A/B
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Calculated)
84kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human DYRK1A/B (Phospho-Tyr321/273)
特异性
This antibody detects endogenous levels of DYRK1A/B (Phospho-Tyr321/273) at Human, Mouse,Rat
基因名称
DYRK1A DYRK MNB MNBH
蛋白名称
DYRK1A/B (Phospho-Tyr321/273)
别名
Dual specificity tyrosine-phosphorylation-regulated kinase 1A;Dual specificity YAK1-related kinase;HP86;Protein kinase minibrain homolog;MNBH;hMNB;
Organism-1
Human
基因ID-1
1859
SwissProt-1
Q13627
Organism-2
Mouse
基因ID-2
13548
SwissProt-2
Q61214
Organism-3
Rat
基因ID-3
25255
SwissProt-3
Q63470
背景
This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' co
细胞定位
Nucleus . Nucleus speckle .
