PEPC (Phospho Ser15) Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612369

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商品描述
  • 靶点-Target

    phosphoenolpyruvate carboxylase

  • 反应性

    A. comosus,A. thaliana,H. vulgare,J. curcas,M. crystallinum,N. tabacum,Z. mays,T. weissfloggi,

  • 应用

    WB,ELISA,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    105-110kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

  • 组成

    PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Polyclonal

  • 免疫原

    Synthetic Peptide of PEPC (Phospho Ser15)

  • 特异性

    The antibody detects endogenous PEPC (Phospho Ser15) protein.

  • 基因名称

    PGC

  • 蛋白名称

    Phosphoenolpyruvate carboxylase

  • 别名

    PGC;Gastricsin;Pepsinogen C

  • 背景

    This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009],

  • 细胞定位

    Secreted.