PDK1 (Phospho Thr338) rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612367

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商品描述
  • 靶点-Target

    PDK1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    50kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human PDHK1 (Phospho Thr338)

  • 特异性

    This antibody detects endogenous levels of Human,Mouse,Rat PDHK1 (Phospho Thr338)

  • 基因名称

    PDK1 PDHK1

  • 蛋白名称

    PDHK1 (Phospho Thr338)

  • 别名

    [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial;Pyruvate dehydrogenase kinase isoform 1;

  • Organism-1

    Human

  • 基因ID-1

    5163

  • SwissProt-1

    Q15118

  • Organism-2

    Mouse

  • 基因ID-2

    228026

  • SwissProt-2

    Q8BFP9

  • Organism-3

    Rat

  • SwissProt-3

    Q63065

  • 背景

    Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013],

  • 细胞定位

    Mitochondrion matrix .