Dab1 (Phospho Tyr220) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612356
- 产品信息
商品描述
靶点-Target
Dab1
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
80kD
推荐稀释比
WB 1:1000-2000;ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Dab1 (Phospho Tyr220)
特异性
This antibody detects endogenous levels of Human,Mouse,Rat Dab1 (Phospho Tyr220)
基因名称
DAB1
蛋白名称
Dab1 (Phospho Tyr220)
别名
DAB1;Disabled homolog 1
Organism-1
Human
基因ID-1
1600
SwissProt-1
O75553
Organism-2
Mouse
基因ID-2
13131
SwissProt-2
P97318
Organism-3
Rat
基因ID-3
266729
SwissProt-3
Q8CJH2
背景
domain:The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.,function:Adapter molecule functioning in neural development. May regulate SIAH1 activity.,PTM:Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.,similarity:Contains 1 PID domain.,subunit:Associates with the SH2 domains of SRC, FYN and ABL. Interacts with DAB2IP and SIAH1 (By similarity). Interacts with LRP1.,





