Dab1 (Phospho Tyr220) rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612356

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商品描述
  • 靶点-Target

    Dab1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    80kD

  • 推荐稀释比

    WB 1:1000-2000;ELISA 1:5000-20000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human Dab1 (Phospho Tyr220)

  • 特异性

    This antibody detects endogenous levels of Human,Mouse,Rat Dab1 (Phospho Tyr220)

  • 基因名称

    DAB1

  • 蛋白名称

    Dab1 (Phospho Tyr220)

  • 别名

    DAB1;Disabled homolog 1

  • Organism-1

    Human

  • 基因ID-1

    1600

  • SwissProt-1

    O75553

  • Organism-2

    Mouse

  • 基因ID-2

    13131

  • SwissProt-2

    P97318

  • Organism-3

    Rat

  • 基因ID-3

    266729

  • SwissProt-3

    Q8CJH2

  • 背景

    domain:The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.,function:Adapter molecule functioning in neural development. May regulate SIAH1 activity.,PTM:Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.,similarity:Contains 1 PID domain.,subunit:Associates with the SH2 domains of SRC, FYN and ABL. Interacts with DAB2IP and SIAH1 (By similarity). Interacts with LRP1.,