Rac1/CDC42 (Phospho Ser71) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612355
- 产品信息
商品描述
靶点-Target
Rac1/CDC42
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Calculated)
21kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Rac1/CDC42 (Phospho Ser71)
特异性
This antibody detects endogenous levels of Human,Mouse,Rat Rac1/CDC42 (Phospho Ser71)
基因名称
RAC1 TC25 MIG5
蛋白名称
Rac1/CDC42 (Phospho Ser71)
别名
Ras-related C3 botulinum toxin substrate 1;Cell migration-inducing gene 5 protein;Ras-like protein TC25;p21-Rac1;
Organism-1
Human
基因ID-1
5879
SwissProt-1
P63000;P15153;P60763;P60953
Organism-2
Mouse
基因ID-2
19353
SwissProt-2
P63001
Organism-3
Rat
基因ID-3
363875
SwissProt-3
Q6RUV5
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome . Cytoplasm . Cell projection, lamellipodium . Cell projection, dendrite . Cell junction, synapse . Nucleus . Inner surface of plasma membrane possibly with attachment requiring prenylation of the C-terminal cysteine (PubMed:1903399). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Found in the ruffled border (a late endosomal-like compartment in the plasma membrane) of bone-resorbing osteoclasts. Localizes to the lamellipodium in a SH3RF1-dependent manner (By similarity). In macrophages, cytoplasmic location increases upon CSF1 stimulation (By similarity). Activation by GTP-binding promotes nuclear localization (PubMed:12551911). .





