Rac1/CDC42 (Phospho Ser71) rabbit pAb

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612355

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商品描述
  • 靶点-Target

    Rac1/CDC42

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Calculated)

    21kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human Rac1/CDC42 (Phospho Ser71)

  • 特异性

    This antibody detects endogenous levels of Human,Mouse,Rat Rac1/CDC42 (Phospho Ser71)

  • 基因名称

    RAC1 TC25 MIG5

  • 蛋白名称

    Rac1/CDC42 (Phospho Ser71)

  • 别名

    Ras-related C3 botulinum toxin substrate 1;Cell migration-inducing gene 5 protein;Ras-like protein TC25;p21-Rac1;

  • Organism-1

    Human

  • 基因ID-1

    5879

  • SwissProt-1

    P63000;P15153;P60763;P60953

  • Organism-2

    Mouse

  • 基因ID-2

    19353

  • SwissProt-2

    P63001

  • Organism-3

    Rat

  • 基因ID-3

    363875

  • SwissProt-3

    Q6RUV5

  • 细胞定位

    Cell membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome . Cytoplasm . Cell projection, lamellipodium . Cell projection, dendrite . Cell junction, synapse . Nucleus . Inner surface of plasma membrane possibly with attachment requiring prenylation of the C-terminal cysteine (PubMed:1903399). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Found in the ruffled border (a late endosomal-like compartment in the plasma membrane) of bone-resorbing osteoclasts. Localizes to the lamellipodium in a SH3RF1-dependent manner (By similarity). In macrophages, cytoplasmic location increases upon CSF1 stimulation (By similarity). Activation by GTP-binding promotes nuclear localization (PubMed:12551911). .