Tyk 2 (Phospho Tyr292) rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612352

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商品描述
  • 靶点-Target

    Tyk 2

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    130kD

  • 推荐稀释比

    WB 1:1000-2000;ELISA 1:5000-20000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human Tyk 2 (Phospho Tyr292)

  • 特异性

    This antibody detects endogenous levels of Human Tyk 2 (Phospho Tyr292)

  • 基因名称

    TYK2

  • 蛋白名称

    Tyk 2 (Phospho Tyr292)

  • 别名

    Non-receptor tyrosine-protein kinase TYK2;

  • Organism-1

    Human

  • 基因ID-1

    7297

  • SwissProt-1

    P29597

  • Organism-2

    Mouse

  • SwissProt-2

    Q9R117

  • 背景

    tyrosine kinase 2(TYK2) Homo sapiens This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008],