GABBR2 (Phospho Ser893) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612339
- 产品信息
商品描述
靶点-Target
GABBR2
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
105kD
推荐稀释比
WB 1:1000-2000;ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human GABBR2 (Phospho Ser893)
特异性
This antibody detects endogenous levels of Human,Mouse,Rat GABBR2 (Phospho Ser893)
基因名称
GABBR2 GPR51 GPRC3B
蛋白名称
GABBR2 (Phospho Ser893)
别名
Gamma-aminobutyric acid type B receptor subunit 2;GABA-B receptor 2;GABA-B-R2;GABA-BR2;GABABR2;Gb2;G-protein coupled receptor 51;HG20;
Organism-1
Human
基因ID-1
9568
SwissProt-1
O75899
Organism-2
Mouse
基因ID-2
242425
SwissProt-2
Q80T41
Organism-3
Rat
基因ID-3
83633
SwissProt-3
O88871
背景
The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010],
细胞定位
Cell membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Coexpression of GABBR1 and GABBR2 is required for GABBR1 maturation and transport to the plasma membrane. In contrast, GABBR2 does not depend on GABBR1 for transport to the cell membrane. .





