IP3 Receptor (Phospho Tyr353) rabbit pAb

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612335

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商品描述
  • 靶点-Target

    IP3 Receptor

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    320kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human IP3 Receptor (Phospho Tyr353)

  • 特异性

    This antibody detects endogenous levels of Human,Mouse,Rat IP3 Receptor (Phospho Tyr353)

  • 基因名称

    ITPR1 INSP3R1

  • 蛋白名称

    IP3 Receptor (Phospho Tyr353)

  • 别名

    Inositol 1,4,5-trisphosphate receptor type 1;IP3 receptor isoform 1;IP3R 1;InsP3R1;Type 1 inositol 1,4,5-trisphosphate receptor;Type 1 InsP3 receptor;

  • Organism-1

    Human

  • 基因ID-1

    3708

  • SwissProt-1

    Q14643

  • Organism-2

    Mouse

  • 基因ID-2

    16438

  • SwissProt-2

    P11881

  • Organism-3

    Rat

  • 基因ID-3

    25262

  • SwissProt-3

    P29994

  • 背景

    This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009],

  • 细胞定位

    Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cytoplasmic vesicle, secretory vesicle membrane ; Multi-pass membrane protein . Cytoplasm, perinuclear region . Endoplasmic reticulum and secretory granules (By similarity). .