FGF-2 Polyclonal Antibody
¥680.00
TOP2A (Phospho Ser1213) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612322
- 产品信息
商品描述
靶点-Target
TOP2A
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
174kD
推荐稀释比
WB 1:1000-2000;ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human TOP2A (Phospho Ser1213)
特异性
This antibody detects endogenous levels of Human TOP2A (Phospho Ser1213)
基因名称
TOP2A TOP2
蛋白名称
TOP2A (Phospho Ser1213)
别名
DNA topoisomerase 2-alpha;DNA topoisomerase II, alpha isozyme;
Organism-1
Human
基因ID-1
7153
SwissProt-1
P11388
Organism-2
Mouse
基因ID-2
21973
SwissProt-2
Q01320
Organism-3
Rat
基因ID-3
360243
SwissProt-3
P41516
背景
catalytic activity:ATP-dependent breakage, passage and rejoining of double-stranded DNA.,enzyme regulation:Specifically inhibited by the intercalating agent amsacrine.,function:Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.,miscellaneous:Eukaryotic topoisomerase I and II can relax both negative and positive supercoils, whereas prokaryotic enzymes relax only negative supercoils.,PTM:Phosphorylation has no effect on catalytic activity.,similarity:Belongs to the type II topoisomerase family.,subcellular location:Generally located in the nucleoplasm.,subunit:Homodimer. Interacts with COPS5.,
细胞定位
Cytoplasm . Nucleus, nucleoplasm . Nucleus . Nucleus, nucleolus .
