Smad2 (Phospho Ser245) rabbit pAb

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612318

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商品描述
  • 靶点-Target

    Smad2

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    55kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human Smad2 (Phospho Ser245)

  • 特异性

    This antibody detects endogenous levels of Human,Mouse,Rat Smad2 (Phospho Ser245)

  • 基因名称

    SMAD2 MADH2 MADR2

  • 蛋白名称

    Smad2 (Phospho Ser245)

  • 别名

    Mothers against decapentaplegic homolog 2;MAD homolog 2;Mothers against DPP homolog 2;JV18-1;Mad-related protein 2;hMAD-2;SMAD family member 2;SMAD 2;Smad2;hSMAD2;

  • Organism-1

    Human

  • 基因ID-1

    4087

  • SwissProt-1

    Q15796

  • Organism-2

    Mouse

  • 基因ID-2

    17126

  • SwissProt-2

    Q62432

  • Organism-3

    Rat

  • 基因ID-3

    29357

  • SwissProt-3

    O70436

  • 细胞定位

    Cytoplasm . Nucleus . Cytoplasmic and nuclear in the absence of TGF-beta. On TGF-beta stimulation, migrates to the nucleus when complexed with SMAD4 (PubMed:9865696, PubMed:21145499). On dephosphorylation by phosphatase PPM1A, released from the SMAD2/SMAD4 complex, and exported out of the nucleus by interaction with RANBP1 (PubMed:16751101, PubMed:19289081). Localized mainly to the nucleus in the early stages of embryo development with expression becoming evident in the cytoplasm at the blastocyst and epiblast stages (By similarity). .