Smad2 (Phospho Ser255) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612317
- 产品信息
商品描述
靶点-Target
Smad2
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
55kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Smad2 (Phospho Ser255)
特异性
This antibody detects endogenous levels of Human,Mouse,Rat Smad2 (Phospho Ser255)
基因名称
SMAD2 MADH2 MADR2
蛋白名称
Smad2 (Phospho Ser255)
别名
Mothers against decapentaplegic homolog 2;MAD homolog 2;Mothers against DPP homolog 2;JV18-1;Mad-related protein 2;hMAD-2;SMAD family member 2;SMAD 2;Smad2;hSMAD2;
Organism-1
Human
基因ID-1
4087
SwissProt-1
Q15796
Organism-2
Mouse
基因ID-2
17126
SwissProt-2
Q62432
Organism-3
Rat
基因ID-3
29357
SwissProt-3
O70436
细胞定位
Cytoplasm . Nucleus . Cytoplasmic and nuclear in the absence of TGF-beta. On TGF-beta stimulation, migrates to the nucleus when complexed with SMAD4 (PubMed:9865696, PubMed:21145499). On dephosphorylation by phosphatase PPM1A, released from the SMAD2/SMAD4 complex, and exported out of the nucleus by interaction with RANBP1 (PubMed:16751101, PubMed:19289081). Localized mainly to the nucleus in the early stages of embryo development with expression becoming evident in the cytoplasm at the blastocyst and epiblast stages (By similarity). .





