YB1 (Phospho Ser102) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612295
- 产品信息
商品描述
靶点-Target
YB1
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
30kD
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human YB1 (Ser102)
特异性
This antibody detects endogenous levels of Human Mouse YB1 (phospho-Ser102)
基因名称
TPSAB1 TPS1 TPS2 TPSB1
蛋白名称
YB1 (Ser102)
别名
Tryptase alpha/beta-1;Tryptase-1;Tryptase I;Tryptase alpha-1;
Organism-1
Human
基因ID-1
7177
SwissProt-1
Q15661
Organism-2
Mouse
基因ID-2
100503895
SwissProt-2
Q02844
Organism-3
Rat
基因ID-3
54271
SwissProt-3
P27435
背景
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate gene
细胞定位
Secreted. Released from the secretory granules upon mast cell activation. .





