TTF-1 (Phospho Ser327) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612281
- 产品信息
商品描述
靶点-Target
TTF-1
反应性
Human,Rat,Mouse,
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
38kD
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human TTF-1 (Ser327)
特异性
This antibody detects endogenous levels of Human TTF-1 (phospho-Ser327)
基因名称
NKX2-1 NKX2A TITF1 TTF1
蛋白名称
TTF-1 (Ser327)
别名
Homeobox protein Nkx-2.1;Homeobox protein NK-2 homolog A;Thyroid nuclear factor 1;Thyroid transcription factor 1;TTF-1;
Organism-1
Human
基因ID-1
7080
SwissProt-1
P43699
Organism-2
Mouse
基因ID-2
21869
SwissProt-2
P50220
Organism-3
Rat
SwissProt-3
P23441
背景
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014],
细胞定位
Nucleus .





