TTF-1 (Phospho Ser327) rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612281

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商品描述
  • 靶点-Target

    TTF-1

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    38kD

  • 推荐稀释比

    WB 1:1000-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized phosho peptide around human TTF-1 (Ser327)

  • 特异性

    This antibody detects endogenous levels of Human TTF-1 (phospho-Ser327)

  • 基因名称

    NKX2-1 NKX2A TITF1 TTF1

  • 蛋白名称

    TTF-1 (Ser327)

  • 别名

    Homeobox protein Nkx-2.1;Homeobox protein NK-2 homolog A;Thyroid nuclear factor 1;Thyroid transcription factor 1;TTF-1;

  • Organism-1

    Human

  • 基因ID-1

    7080

  • SwissProt-1

    P43699

  • Organism-2

    Mouse

  • 基因ID-2

    21869

  • SwissProt-2

    P50220

  • Organism-3

    Rat

  • SwissProt-3

    P23441

  • 背景

    This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014],

  • 细胞定位

    Nucleus .