TORC1/CRTC1 (Phospho Ser151) rabbit pAb

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612278

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商品描述
  • 靶点-Target

    TORC1

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    70kD

  • 推荐稀释比

    WB 1:1000-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized phosho peptide around human TORC1 and CRTC1 (Ser151)

  • 特异性

    This antibody detects endogenous levels of Human TORC1 or CRTC1 (phospho-Ser151)

  • 基因名称

    CRTC1 KIAA0616 MECT1 TORC1 WAMTP1

  • 蛋白名称

    TORC1/CRTC1 (Ser151)

  • 别名

    CREB-regulated transcription coactivator 1;Mucoepidermoid carcinoma translocated protein 1;Transducer of regulated cAMP response element-binding protein 1;TORC-1;Transducer of CREB protein 1;

  • Organism-1

    Human

  • 基因ID-1

    23373

  • SwissProt-1

    Q6UUV9

  • Organism-2

    Mouse

  • 基因ID-2

    382056

  • SwissProt-2

    Q68ED7

  • Organism-3

    Rat

  • 基因ID-3

    684527

  • SwissProt-3

    Q157S1

  • 细胞定位

    Cytoplasm . Nucleus . Cytoplasmic when phosphorylated by SIK or AMPK and when sequestered by 14-3-3 proteins (PubMed:16817901). Translocated to the nucleus on Ser-151 dephosphorylation, instigated by a number of factors including calcium ion and cAMP levels (PubMed:15589160). Light stimulation triggers a nuclear accumulation in the suprachiasmatic nucleus (SCN) of the brain (By similarity). .