FGF-2 Polyclonal Antibody
¥680.00
TNK1 (Phospho Tyr277) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612276
- 产品信息
商品描述
靶点-Target
TNK1
反应性
Human,Rat,Mouse,
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
75kD
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human TNK1 (Tyr277)
特异性
This antibody detects endogenous levels of Human TNK1 (phospho-Tyr277)
基因名称
TNK1
蛋白名称
TNK1 (Tyr277)
别名
Non-receptor tyrosine-protein kinase TNK1;CD38 negative kinase 1;
Organism-1
Human
基因ID-1
8711
SwissProt-1
Q13470
Organism-2
Mouse
基因ID-2
83813
SwissProt-2
Q99ML2
背景
The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
细胞定位
Cytoplasm . Membrane ; Peripheral membrane protein .
