FGF-2 Polyclonal Antibody
¥680.00
TBK1/NAK (Phospho Ser172) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612272
- 产品信息
商品描述
靶点-Target
TBK1
反应性
Human,Mouse
应用
ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
80kD
推荐稀释比
ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human TBK1 and NAK (Ser172)
特异性
This antibody detects endogenous levels of Human Mouse TBK1/NAK (phospho-Ser172)
基因名称
TBK1 NAK
蛋白名称
TBK1/NAK (Ser172)
别名
Serine/threonine-protein kinase TBK1;NF-kappa-B-activating kinase;T2K;TANK-binding kinase 1;
Organism-1
Human
基因ID-1
29110
SwissProt-1
Q9UHD2
Organism-2
Mouse
基因ID-2
56480
SwissProt-2
Q9WUN2
背景
The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010],
细胞定位
Cytoplasm . Upon mitogen stimulation or triggering of the immune system, TBK1 is recruited to the exocyst by EXOC2. .
