FGF-2 Polyclonal Antibody
¥680.00
SGK3 (Phospho Thr320) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612237
- 产品信息
商品描述
靶点-Target
SGK3
反应性
Human,Rat,Mouse,
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
54kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human SGK3 (Thr320)
特异性
This antibody detects endogenous levels of Human SGK3 (phospho-Thr320)
基因名称
SGK3 CISK SGKL
蛋白名称
SGK3 (Thr320)
别名
Serine/threonine-protein kinase Sgk3;Cytokine-independent survival kinase;Serum/glucocorticoid-regulated kinase 3;Serum/glucocorticoid-regulated kinase-like;
Organism-1
Human
基因ID-1
100533105
SwissProt-1
Q96BR1
Organism-2
Mouse
基因ID-2
170755
SwissProt-2
Q9ERE3
Organism-3
Rat
SwissProt-3
Q8R4V0
背景
This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasmic vesicle . Early endosome. Recycling endosome. Endosomal localization is a prerequisite for complete kinase activity. It is essential for its colocalization with the kinase responsible for phosphorylating Ser-486 thus allowing PDPK1 phosphorylation of Thr-320 resulting in complete activation of SGK3. Localized in vesicle-like structures and in the early endosome. Colocalizes with SLC9A3/NHE3 in the recycling endosomes.
