FGF-2 Polyclonal Antibody
¥680.00
SEK1/MKK4 (Phospho Ser257/Thr261) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612232
- 产品信息
商品描述
靶点-Target
MEK-4
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
44kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human SEK1 (Ser257 and Thr261)
特异性
This antibody detects endogenous levels of Human Mouse Rat SEK1/MKK4 (phospho-Ser257 or Thr261)
基因名称
MAP2K4 JNKK1 MEK4 MKK4 PRKMK4 SEK1 SERK1 SKK1
蛋白名称
SEK1/MKK4 (Ser257/Thr261)
别名
Dual specificity mitogen-activated protein kinase kinase 4;MAP kinase kinase 4;MAPKK 4;JNK-activating kinase 1;MAPK/ERK kinase 4;MEK 4;SAPK/ERK kinase 1;SEK1;Stress-activated protein kinase kinase 1;SAPK kinase 1;SAPKK-1;SAPKK1;c-Jun N-terminal kinase kinase 1;JNKK;
Organism-1
Human
基因ID-1
6416
SwissProt-1
P45985
Organism-2
Mouse
基因ID-2
26398
SwissProt-2
P47809
背景
This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
细胞定位
Cytoplasm . Nucleus .
