RIP3 (Phospho Ser227) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612220
- 产品信息
商品描述
靶点-Target
RIP3
反应性
Human
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
56-70kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human RIP3 (Ser227)
特异性
This antibody detects endogenous levels of Human RIP3 (phospho-Ser227)
基因名称
RIPK3 RIP3
蛋白名称
RIP3 (Ser227)
别名
Receptor-interacting serine/threonine-protein kinase 3;RIP-like protein kinase 3;Receptor-interacting protein 3;RIP-3;
Organism-1
Human
基因ID-1
11035
SwissProt-1
Q9Y572
Organism-2
Mouse
SwissProt-2
Q9QZL0
Organism-3
Rat
基因ID-3
246240
SwissProt-3
Q9Z2P5
背景
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, cytosol . Nucleus . Mainly cytoplasmic. Present in the nucleus in response to influenza A virus (IAV) infection. .





