FGF-2 Polyclonal Antibody
¥680.00
Rev-erbα (Phospho Ser55/59) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612217
- 产品信息
商品描述
靶点-Target
Rev-erbα
反应性
Human,Rat,Mouse,
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
67kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human Rev-erbα (Ser55 and 59)
特异性
This antibody detects endogenous levels of Human Rev-erbα (phospho-Ser55 or 59)
基因名称
NR1D1 EAR1 HREV THRAL
蛋白名称
Rev-erbα (Ser55/59)
别名
Nuclear receptor subfamily 1 group D member 1;Rev-erbA-alpha;V-erbA-related protein 1;EAR-1;
Organism-1
Human
基因ID-1
9572
SwissProt-1
P20393
Organism-2
Mouse
基因ID-2
217166
SwissProt-2
Q3UV55
Organism-3
Rat
基因ID-3
252917
SwissProt-3
Q63503
背景
This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes. [provided by RefSeq, Jan 2013],
细胞定位
Nucleus . Cytoplasm . Cell projection, dendrite . Cell projection, dendritic spine . Localizes to the cytoplasm, dendrites and dendritic spine in the presence of OPHN1. Localizes predominantly to the nucleus at ZT8 whereas it is cytoplasmic at ZT20. Phosphorylation by CSNK1E enhances its cytoplasmic localization. .
