REPS1 (Phospho Ser709) rabbit pAb

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612216

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商品描述
  • 靶点-Target

    REPS1

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    80kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized phosho peptide around human REPS1 (Ser709)

  • 特异性

    This antibody detects endogenous levels of Human REPS1 (phospho-Ser709)

  • 基因名称

    REPS1

  • 蛋白名称

    REPS1 (Ser709)

  • 别名

    RalBP1-associated Eps domain-containing protein 1;RalBP1-interacting protein 1;

  • Organism-1

    Human

  • 基因ID-1

    85021

  • SwissProt-1

    Q96D71

  • Organism-2

    Mouse

  • 基因ID-2

    19707

  • SwissProt-2

    O54916

  • 背景

    This gene encodes a signaling adaptor protein with two EH domains that interacts with proteins that participate in signaling, endocytosis and cytoskeletal changes. The encoded protein has been found in association with intersectin 1 and Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1 when intersectin 1 was isolated from clathrin-coated pits. The encoded protein has also been shown to interact with amphiphysin, a cytoplasmic protein at the surface of synaptic vesicles. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014],

  • 细胞定位

    Membrane, clathrin-coated pit . Colocalize with ITSN1 at the plasma membrane in structures that are most probably clathrin-coated pits.