PSD95 (Phospho Ser295) rabbit pAb

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612206

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商品描述
  • 靶点-Target

    PSD95

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    95kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized phosho peptide around human PSD95 (Ser295)

  • 特异性

    This antibody detects endogenous levels of Human Mouse Rat PSD95 (phospho-Ser295)

  • 基因名称

    DLG4 PSD95

  • 蛋白名称

    PSD95 (Ser295)

  • 别名

    Disks large homolog 4;Postsynaptic density protein 95;PSD-95;Synapse-associated protein 90;SAP-90;SAP90;

  • Organism-1

    Human

  • 基因ID-1

    1742

  • SwissProt-1

    P78352

  • Organism-2

    Mouse

  • 基因ID-2

    13385

  • SwissProt-2

    Q62108

  • Organism-3

    Rat

  • 基因ID-3

    29495

  • SwissProt-3

    P31016

  • 背景

    This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cell junction, synapse, postsynaptic density . Cell junction, synapse . Cytoplasm . Cell projection, axon . Cell projection, dendritic spine . Cell projection, dendrite . Cell junction, synapse, presynapse . High levels in postsynaptic density of neurons in the forebrain. Also in presynaptic region of inhibitory synapses formed by cerebellar basket cells on axon hillocks of Purkinje cells. Suppression of neuronal activity induces synaptic accumulation and clustering of DLG4. .