PDGF Receptor α (Phospho Tyr1018) rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612192

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商品描述
  • 靶点-Target

    PDGF Receptor α

  • 反应性

    Human,Mouse

  • 应用

    WB,ELISA,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    180kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized phosho peptide around human PDGF Receptor α (Tyr1018)

  • 特异性

    This antibody detects endogenous levels of Human Mouse PDGF Receptor α (phospho-Tyr1018)

  • 基因名称

    PDGFRA PDGFR2 RHEPDGFRA

  • 蛋白名称

    PDGF Receptor α (Tyr1018)

  • 别名

    Platelet-derived growth factor receptor alpha;PDGF-R-alpha;PDGFR-alpha;Alpha platelet-derived growth factor receptor;Alpha-type platelet-derived growth factor receptor;CD140 antigen-like family member A;CD140a antigen;Platelet-derived growth factor alpha receptor;Platelet-derived growth factor receptor 2;PDGFR-2;CD antigen CD140a;

  • Organism-1

    Human

  • 基因ID-1

    5156

  • SwissProt-1

    P16234

  • Organism-2

    Mouse

  • 基因ID-2

    18595

  • SwissProt-2

    P26618

  • Organism-3

    Rat

  • 基因ID-3

    25267

  • SwissProt-3

    P20786

  • 背景

    This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012],

  • 细胞定位

    Cell membrane ; Single-pass type I membrane protein . Cell projection, cilium . Golgi apparatus .