p70 S6 Kinase (Phospho Thr389) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612187
- 产品信息
商品描述
靶点-Target
p70 S6 kinase α
反应性
Human,Mouse,Rat,Bovine
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
59kD
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human p70 S6 Kinase (Thr389)
特异性
This antibody detects endogenous levels of Human Mouse Rat p70 S6 Kinase (phospho-Thr389)
基因名称
RPS6KB1 STK14A P70S6K
蛋白名称
Ribosomal protein S6 kinase beta-1,p70 S6 Kinase (Thr389)
别名
Ribosomal protein S6 kinase beta-1;S6K-beta-1;S6K1;70 kDa ribosomal protein S6 kinase 1;P70S6K1;p70-S6K 1;Ribosomal protein S6 kinase I;Serine/threonine-protein kinase 14A;p70 ribosomal S6 kinase alpha;p70 S6 kinase alpha;p70 S6K-alpha;p70 S6KA;
Organism-1
Human
基因ID-1
6198
SwissProt-1
P23443
Organism-2
Mouse
基因ID-2
72508
SwissProt-2
Q8BSK8
Organism-3
Rat
基因ID-3
83840
SwissProt-3
P67999
背景
ribosomal protein S6 kinase B1(RPS6KB1) Homo sapiens This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013],
细胞定位
Cell junction, synapse, synaptosome . Mitochondrion outer membrane. Mitochondrion. Colocalizes with URI1 at mitochondrion.; [Isoform Alpha I]: Nucleus. Cytoplasm.; [Isoform Alpha II]: Cytoplasm.





