p63 (Phospho Ser160/162) rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612186

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商品描述
  • 靶点-Target

    p40/p63

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    63kD

  • 推荐稀释比

    WB 1:1000-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized phosho peptide around human p63 (Ser160 and 162)

  • 特异性

    This antibody detects endogenous levels of Human p63 (phospho-Ser160 or 162)

  • 基因名称

    TP63 KET P63 P73H P73L TP73L

  • 蛋白名称

    p63 (Ser160/162)

  • 别名

    Tumor protein 63;p63;Chronic ulcerative stomatitis protein;CUSP;Keratinocyte transcription factor KET;Transformation-related protein 63;TP63;Tumor protein p73-like;p73L;p40;p51;

  • Organism-1

    Human

  • 基因ID-1

    8626

  • SwissProt-1

    Q9H3D4

  • Organism-2

    Mouse

  • 基因ID-2

    22061

  • SwissProt-2

    O88898

  • Organism-3

    Rat

  • 基因ID-3

    246334

  • SwissProt-3

    Q9JJP6

  • 背景

    tumor protein p63(TP63) Homo sapiens This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrim

  • 细胞定位

    Nucleus .