Numb (Phospho Ser276) rabbit pAb

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612184

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商品描述
  • 靶点-Target

    Numb

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    70kD

  • 推荐稀释比

    WB 1:1000-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized phosho peptide around human Numb (Ser276)

  • 特异性

    This antibody detects endogenous levels of Human Numb (phospho-Ser276)

  • 基因名称

    NUMB

  • 蛋白名称

    Numb (Ser276)

  • 别名

    Protein numb homolog;h-Numb;Protein S171;

  • Organism-1

    Human

  • 基因ID-1

    8650

  • SwissProt-1

    P49757

  • Organism-2

    Mouse

  • 基因ID-2

    18222

  • SwissProt-2

    Q9QZS3

  • Organism-3

    Rat

  • SwissProt-3

    Q2LC84

  • 背景

    The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],

  • 细胞定位

    Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Localizes to perinuclear endosomes in an AAK1-dependent manner. .