FGF-2 Polyclonal Antibody
¥680.00
MKK7 (Phospho Ser271/Thr275) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612167
- 产品信息
商品描述
靶点-Target
MKK7
反应性
Human,Rat,Mouse,
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
47kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human MKK7 (Ser271 and Thr275)
特异性
This antibody detects endogenous levels of Human MKK7 (phospho-Ser271 or Thr275)
基因名称
MAP2K7 JNKK2 MEK7 MKK7 PRKMK7 SKK4
蛋白名称
MKK7 (Ser271/Thr275)
别名
Dual specificity mitogen-activated protein kinase kinase 7;MAP kinase kinase 7;MAPKK 7;JNK-activating kinase 2;MAPK/ERK kinase 7;MEK 7;Stress-activated protein kinase kinase 4;SAPK kinase 4;SAPKK-4;SAPKK4;c-Jun N-terminal kinase kinase 2;JNK kinase 2;JNKK 2;
Organism-1
Human
基因ID-1
5609
SwissProt-1
O14733
Organism-2
Mouse
基因ID-2
26400
SwissProt-2
Q8CE90
Organism-3
Rat
基因ID-3
363855
SwissProt-3
Q4KSH7
背景
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
细胞定位
Nucleus. Cytoplasm .
