Lyn (Phospho Tyr507) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612153
- 产品信息
商品描述
靶点-Target
Lyn
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
58kD
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human Lyn (Tyr507)
特异性
This antibody detects endogenous levels of Human Mouse Lyn (phospho-Tyr507)
基因名称
LYN JTK8
蛋白名称
Lyn (Tyr507)
别名
Tyrosine-protein kinase Lyn;Lck/Yes-related novel protein tyrosine kinase;V-yes-1 Yamaguchi sarcoma viral related oncogene homolog;p53Lyn;p56Lyn;
Organism-1
Human
基因ID-1
4067
SwissProt-1
P07948
Organism-2
Mouse
基因ID-2
17096
SwissProt-2
P25911
Organism-3
Rat
基因ID-3
81515
SwissProt-3
Q07014
背景
This gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011],
细胞定位
Cell membrane. Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus. Membrane ; Lipid-anchor . Accumulates in the nucleus by inhibition of CRM1-mediated nuclear export. Nuclear accumulation is increased by inhibition of its kinase activity. The trafficking from the Golgi apparatus to the plasma membrane occurs in a kinase domain-dependent but kinase activity independent manner and is mediated by exocytic vesicular transport. Detected on plasma membrane lipid rafts.





