FGF-2 Polyclonal Antibody
¥680.00
LCP1 (Phospho Tyr28) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612148
- 产品信息
商品描述
靶点-Target
LCP1
反应性
Human,Rat,Mouse,
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
68kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human LCP1 (Tyr28)
特异性
This antibody detects endogenous levels of Human LCP1 (phospho-Tyr28)
基因名称
LCP1 PLS2
蛋白名称
LCP1 (Tyr28)
别名
Plastin-2;L-plastin;LC64P;Lymphocyte cytosolic protein 1;LCP-1;
Organism-1
Human
基因ID-1
3936
SwissProt-1
P13796
Organism-2
Mouse
基因ID-2
18826
SwissProt-2
Q61233
背景
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, cytoskeleton . Cell junction . Cell projection . Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side . Relocalizes to the immunological synapse between peripheral blood T-lymphocytes and antibody-presenting cells in response to costimulation through TCR/CD3 and CD2 or CD28 (PubMed:17294403). Associated with the actin cytoskeleton at membrane ruffles. Relocalizes to actin-rich cell projections upon serine phosphorylation (PubMed:16636079). .
