FGF-2 Polyclonal Antibody
¥680.00
IGF-I Receptor β (Phospho Tyr1316) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612126
- 产品信息
商品描述
靶点-Target
IGF-1R
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
pro:155kD,recetor beta:95kD
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human IGF-I Receptor β (Tyr1316)
特异性
This antibody detects endogenous levels of Human Mouse IGF-I Receptor β (phospho-Tyr1316)
基因名称
IGF1R
蛋白名称
IGF-I Receptor β (Tyr1316)
别名
Insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;IGF-I receptor;CD antigen CD221;[Cleaved into: Insulin-like growth factor 1 receptor alpha chain;Insulin-like growth factor 1 receptor beta chain]
Organism-1
Human
基因ID-1
3480
SwissProt-1
P08069
Organism-2
Mouse
基因ID-2
16001
SwissProt-2
Q60751
Organism-3
Rat
基因ID-3
25718
SwissProt-3
P24062
背景
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],
细胞定位
Cell membrane ; Single-pass type I membrane protein .
