HNF1α (Phospho Ser247) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612121
- 产品信息
商品描述
靶点-Target
HNF1A
反应性
Human,Rat,Mouse,
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
69kD
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human HNF1α (Ser247)
特异性
This antibody detects endogenous levels of Human HNF1α (phospho-Ser247)
基因名称
HNF1A TCF1
蛋白名称
HNF1α (Ser247)
别名
Hepatocyte nuclear factor 1-alpha;HNF-1-alpha;HNF-1A;Liver-specific transcription factor LF-B1;LFB1;Transcription factor 1;TCF-1;
Organism-1
Human
基因ID-1
6927
SwissProt-1
P20823
Organism-2
Mouse
基因ID-2
21405
SwissProt-2
P22361
Organism-3
Rat
基因ID-3
24817
SwissProt-3
P15257
背景
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],
细胞定位
Nucleus .





