FGF-2 Polyclonal Antibody
¥680.00
GSK-3β (Phospho Thr390) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612117
- 产品信息
商品描述
靶点-Target
GSK3β
反应性
Human,Rat,Mouse,
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
48kD
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human GSK-3β (Thr390)
特异性
This antibody detects endogenous levels of Human GSK-3β (phospho-Thr390)
基因名称
GSK3B
蛋白名称
GSK-3β (Thr390)
别名
Glycogen synthase kinase-3 beta;GSK-3 beta;Serine/threonine-protein kinase GSK3B;
Organism-1
Human
基因ID-1
2932
SwissProt-1
P49841
Organism-2
Mouse
基因ID-2
56637
SwissProt-2
Q9WV60
Organism-3
Rat
基因ID-3
84027
SwissProt-3
P18266
背景
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009],
细胞定位
Cytoplasm . Nucleus . Cell membrane . The phosphorylated form shows localization to cytoplasm and cell membrane (PubMed:20937854). The MEMO1-RHOA-DIAPH1 signaling pathway controls localization of the phosphorylated form to the cell membrane (PubMed:20937854). .
