FGF-2 Polyclonal Antibody
¥680.00
GIT2 (Phospho Tyr392) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612114
- 产品信息
商品描述
靶点-Target
GIT2
反应性
Human,Rat,Mouse,
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
84kD
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human GIT2 (Tyr392)
特异性
This antibody detects endogenous levels of Human GIT2 (phospho-Tyr392)
基因名称
GIT2 KIAA0148
蛋白名称
GIT2 (Tyr392)
别名
ARF GTPase-activating protein GIT2;ARF GAP GIT2;Cool-interacting tyrosine-phosphorylated protein 2;CAT-2;CAT2;G protein-coupled receptor kinase-interactor 2;GRK-interacting protein 2;
Organism-1
Human
基因ID-1
9815
SwissProt-1
Q14161
Organism-2
Mouse
基因ID-2
26431
SwissProt-2
Q9JLQ2
背景
This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G
细胞定位
nucleoplasm,focal adhesion,
