DR6 (Phospho Ser562) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612086
- 产品信息
商品描述
靶点-Target
DR6
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
72kD
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human DR6 (Ser562)
特异性
This antibody detects endogenous levels of Human Mouse Rat DR6 (phospho-Ser562)
基因名称
TNFRSF21 DR6 UNQ437/PRO868
蛋白名称
DR6 (Ser562)
别名
Tumor necrosis factor receptor superfamily member 21;Death receptor 6;CD antigen CD358;
Organism-1
Human
基因ID-1
27242
SwissProt-1
O75509
Organism-2
Mouse
基因ID-2
94185
SwissProt-2
Q9EPU5
背景
This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2013],
细胞定位
Cell membrane ; Single-pass type I membrane protein .





