FGF-2 Polyclonal Antibody
¥680.00
Desmoplakin (Phospho Ser165/166) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612083
- 产品信息
商品描述
靶点-Target
Desmoplakin
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
300kD
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human Desmoplakin (Ser165 and 166)
特异性
This antibody detects endogenous levels of Human Mouse Rat Desmoplakin (phospho-Ser165 or 166)
基因名称
DSP
蛋白名称
Desmoplakin (Ser165/166)
别名
Desmoplakin;DP;250/210 kDa paraneoplastic pemphigus antigen;
Organism-1
Human
基因ID-1
1832
SwissProt-1
P15924
Organism-2
Mouse
基因ID-2
109620
SwissProt-2
E9Q557
背景
This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
细胞定位
Cell junction, desmosome . Cytoplasm, cytoskeleton . Cell membrane . Innermost portion of the desmosomal plaque. Colocalizes with epidermal KRT5-KRT14 and simple KRT8-KRT18 keratins and VIM intermediate filaments network (PubMed:12802069). Localizes at the intercalated disk in cardiomyocytes (By similarity). .
