CYLD (Phospho Ser418) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612079
- 产品信息
商品描述
靶点-Target
CYLD
反应性
Human,Rat,Mouse,
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
105kD
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human CYLD (Ser418)
特异性
This antibody detects endogenous levels of Human CYLD (phospho-Ser418)
基因名称
CYLD CYLD1 KIAA0849 HSPC057
蛋白名称
CYLD (Ser418)
别名
Ubiquitin carboxyl-terminal hydrolase CYLD;Deubiquitinating enzyme CYLD;Ubiquitin thioesterase CYLD;Ubiquitin-specific-processing protease CYLD;
Organism-1
Human
基因ID-1
1540
SwissProt-1
Q9NQC7
Organism-2
Mouse
基因ID-2
74256
SwissProt-2
Q80TQ2
Organism-3
Rat
基因ID-3
312937
SwissProt-3
Q66H62
背景
This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton, cilium basal body . Detected at the microtubule cytoskeleton during interphase. Detected at the midbody during telophase. During metaphase, it remains localized to the centrosome but is also present along the spindle (PubMed:25134987). .





