FGF-2 Polyclonal Antibody
¥680.00
BAP1 (Phospho Ser592) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612047
- 产品信息
商品描述
靶点-Target
BAP1
反应性
Human,Rat,Mouse,
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
80kD
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human BAP1 (Ser592)
特异性
This antibody detects endogenous levels of Human BAP1 (phospho-Ser592)
基因名称
BAP1 KIAA0272 hucep-6
蛋白名称
BAP1 (Ser592)
别名
Ubiquitin carboxyl-terminal hydrolase BAP1;BRCA1-associated protein 1;Cerebral protein 6;
Organism-1
Human
基因ID-1
8314
SwissProt-1
Q92560
Organism-2
Mouse
基因ID-2
104416
SwissProt-2
Q99PU7
Organism-3
Rat
基因ID-3
306257
SwissProt-3
D3ZHS6
背景
This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013],
细胞定位
Cytoplasm . Nucleus . Mainly nuclear. Binds to chromatin. Localizes to the cytoplasm when monoubiquitinated by the E2/E3 hybrid ubiquitin-protein ligase UBE2O (PubMed:24703950). .
