FGF-2 Polyclonal Antibody
¥680.00
53BP1 (Phospho Ser1618) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612028
- 产品信息
商品描述
靶点-Target
53BP1
反应性
Human,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
213kD
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phosho peptide around human 53BP1 (Ser1618)
特异性
This antibody detects endogenous levels of Human Rat 53BP1 (phospho-Ser1618)
基因名称
TP53BP1
蛋白名称
53BP1 (Ser1618)
别名
Tumor suppressor p53-binding protein 1;53BP1;p53-binding protein 1;p53BP1;
Organism-1
Human
基因ID-1
7158
SwissProt-1
Q12888
Organism-2
Mouse
基因ID-2
27223
SwissProt-2
P70399
细胞定位
Nucleus . Chromosome . Chromosome, centromere, kinetochore . Localizes to the nucleus in absence of DNA damage (PubMed:28241136). Following DNA damage, recruited to sites of DNA damage, such as double stand breaks (DSBs): recognizes and binds histone H2A monoubiquitinated at 'Lys-15' (H2AK15Ub) and histone H4 dimethylated at 'Lys-20' (H4K20me2), two histone marks that are present at DSBs sites (PubMed:23333306, PubMed:23760478, PubMed:24703952, PubMed:28241136, PubMed:17190600). Associated with kinetochores during mitosis (By similarity). .
