CaMK2 (Phospho Thr286) Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612025
- 产品信息
商品描述
靶点-Target
CaMK2
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
54kD
推荐稀释比
WB 1:500-2000;ELISA(peptide)1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized pospho peptide derived from human CaMK2 (Phospho-Thr286)
特异性
This antibody detects endogenous pospho levels of human CaMK2 (Phospho-Thr286)
基因名称
CAMK2D CAMKD
蛋白名称
CaMK2 (Phospho-Thr286)
别名
Calcium/calmodulin-dependent protein kinase type II subunit delta;CaM kinase II subunit delta;CaMK-II subunit delta;
Organism-1
Human
基因ID-1
817
SwissProt-1
Q9UQM7;Q13557
背景
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],
细胞定位
Cell junction, synapse . Cell junction, synapse, postsynaptic density . Cell projection, dendritic spine . Cell projection, dendrite . Postsynaptic lipid rafts. .





