Nuclear Receptor NR4A1 (Phospho Ser351) Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612024
- 产品信息
商品描述
靶点-Target
Nur77
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
77kD
推荐稀释比
WB 1:500-2000;ELISA(peptide)1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized pospho peptide derived from human Nuclear Receptor NR4A1 (Phospho-Ser351)
特异性
This antibody detects endogenous pospho levels of human Nuclear Receptor NR4A1 (Phospho-Ser351)
基因名称
NR4A1 GFRP1 HMR NAK1
蛋白名称
Nuclear Receptor NR4A1 (Phospho-Ser351)
别名
Nuclear receptor subfamily 4 group A member 1;Early response protein NAK1;Nuclear hormone receptor NUR/77;Nur77;Orphan nuclear receptor HMR;Orphan nuclear receptor TR3;ST-59;Testicular receptor 3;
Organism-1
Human
基因ID-1
3164
SwissProt-1
P22736
背景
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011],
细胞定位
Nucleus . Cytoplasm . Mitochondrion . Nuclear export to the cytoplasm is XPO1-mediated and positively regulated by IFI27 (PubMed:22427340). Translocation to the mitochondrion upon interaction with RXRA and upon the presence of 9-cis retinoic acid (PubMed:17761950). .





