Trk B (Phospho Y817) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612023
- 产品信息
商品描述
靶点-Target
Trk B
反应性
Human,Mouse,Rat
应用
IHC,IF,WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
145kD
推荐稀释比
IHC 1:50-200;WB 1:500-2000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Trk B (Phospho-Y817)
特异性
This antibody detects endogenous phospho levels of Trk B (Phospho-Y817) Polyclonal Antibody at Human, Mouse, Rat
基因名称
NTRK2 TRKB
蛋白名称
Trk B (Phospho-Y817) Polyclonal Antibody
别名
BDNF/NT-3 growth factors receptor;GP145-TrkB;Trk-B;Neurotrophic tyrosine kinase receptor type 2;TrkB tyrosine kinase;Tropomyosin-related kinase B;
Organism-1
Human
基因ID-1
4915
SwissProt-1
Q16620
背景
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein . Early endosome membrane . Cell projection, axon . Cell projection, dendrite . Cytoplasm, perinuclear region . Cell junction, synapse, postsynaptic density . Internalized to endosomes upon ligand-binding. .





