FGF-2 Polyclonal Antibody
¥680.00
MARK2 (phospho Thr596) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2611966
- 产品信息
商品描述
靶点-Target
MARK2
反应性
Human,Mouse,Rat
应用
IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Calculated)
88kD
推荐稀释比
IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications;
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MARK2 around the phosphorylation site of Thr596. AA range:562-611
特异性
Phospho-MARK2 (T596) Polyclonal Antibody detects endogenous levels of MARK2 protein only when phosphorylated at T596.
基因名称
MARK2
蛋白名称
Serine/threonine-protein kinase MARK2
别名
MARK2;EMK1;Serine/threonine-protein kinase MARK2;ELKL motif kinase 1;EMK-1;MAP/microtubule affinity-regulating kinase 2;PAR1 homolog;PAR1 homolog b;Par-1b;Par1b
Organism-1
Human
基因ID-1
2011
SwissProt-1
Q7KZI7
Organism-2
Mouse
基因ID-2
13728
SwissProt-2
Q05512
Organism-3
Rat
基因ID-3
60328
SwissProt-3
O08679
背景
microtubule affinity regulating kinase 2(MARK2) Homo sapiens This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009],
细胞定位
Cell membrane; Peripheral membrane protein. Cytoplasm. Lateral cell membrane. Cytoplasm, cytoskeleton. Cell projection, dendrite . Cytoplasm . Phosphorylation at Thr-596 by PRKCZ/aPKC and subsequent interaction with 14-3-3 protein YWHAZ promotes relocation from the cell membrane to the cytoplasm.
