FGF-2 Polyclonal Antibody
¥680.00
Synapsin I (phospho Ser605) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2611926
- 产品信息
商品描述
靶点-Target
Synapsin I
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Calculated)
74kD
推荐稀释比
IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Synapsin1 around the phosphorylation site of Ser605. AA range:576-625
特异性
Phospho-Synapsin I (S605) Polyclonal Antibody detects endogenous levels of Synapsin I protein only when phosphorylated at S605.
基因名称
SYN1
蛋白名称
Synapsin-1
别名
SYN1;Synapsin-1;Brain protein 4.1;Synapsin I
Organism-1
Human
基因ID-1
6853
SwissProt-1
P17600
Organism-2
Mouse
基因ID-2
20964
SwissProt-2
O88935
Organism-3
Rat
基因ID-3
24949
SwissProt-3
P09951
背景
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
细胞定位
Cell junction, synapse. Golgi apparatus .
