Dok-2 (phospho Tyr345) Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2611892

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商品描述
  • 靶点-Target

    Dok-2

  • 反应性

    Human,Mouse

  • 应用

    IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Calculated)

    45kD

  • 推荐稀释比

    IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized phospho-peptide around the phosphorylation site of human Dok-2 (phospho Tyr345)

  • 特异性

    Phospho-Dok-2 (Y345) Polyclonal Antibody detects endogenous levels of Dok-2 protein only when phosphorylated at Y345.

  • 基因名称

    DOK2

  • 蛋白名称

    Docking protein 2

  • 别名

    DOK2;Docking protein 2;Downstream of tyrosine kinase 2;p56;dok-2;

  • Organism-1

    Human

  • 基因ID-1

    9046

  • SwissProt-1

    O60496

  • Organism-2

    Mouse

  • 基因ID-2

    13449

  • SwissProt-2

    O70469

  • 背景

    docking protein 2(DOK2) Homo sapiens The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008],

  • 细胞定位

    cytosol,