Fhit (phospho Tyr114) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611891
- 产品信息
商品描述
靶点-Target
Fhit
反应性
Human,Rat,Mouse,
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Calculated)
17kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human FHIT around the phosphorylation site of Tyr114. AA range:80-129
特异性
Phospho-Fhit (Y114) Polyclonal Antibody detects endogenous levels of Fhit protein only when phosphorylated at Y114.
基因名称
FHIT
蛋白名称
Bis(5'-adenosyl)-triphosphatase
别名
FHIT;Bis;5'-adenosyl;-triphosphatase;AP3A hydrolase;AP3Aase;Diadenosine 5';5'''-P1,P3-triphosphate hydrolase;Dinucleosidetriphosphatase;Fragile histidine triad protein
Organism-1
Human
基因ID-1
2272
SwissProt-1
P49789
Organism-2
Mouse
SwissProt-2
O89106
背景
This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009],
细胞定位
Cytoplasm . Mitochondrion . Nucleus .





