FGF-2 Polyclonal Antibody
¥680.00
Claudin-4 (phospho Tyr208) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2611865
- 产品信息
商品描述
靶点-Target
Claudin-4
反应性
Human,Rat,Mouse,
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Calculated)
22kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Claudin 4 around the phosphorylation site of Tyr208. AA range:160-209
特异性
Phospho-Claudin-4 (Y208) Polyclonal Antibody detects endogenous levels of Claudin-4 protein only when phosphorylated at Y208.
基因名称
CLDN4
蛋白名称
Claudin-4
别名
CLDN4;CPER;CPETR1;WBSCR8;Claudin-4;Clostridium perfringens enterotoxin receptor;CPE-R;CPE-receptor;Williams-Beuren syndrome chromosomal region 8 protein
Organism-1
Human
基因ID-1
1364
SwissProt-1
O14493
Organism-2
Mouse
SwissProt-2
O35054
背景
The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013],
细胞定位
Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein . CLDN4 is required for tight junction localization in the kidney. .
