NBK (phospho Ser35) Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2611859

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商品描述
  • 靶点-Target

    NBK

  • 反应性

    Human,Rat,Mouse,

  • 应用

    IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Calculated)

    18kD

  • 推荐稀释比

    IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized phospho-peptide around the phosphorylation site of human NBK (phospho Ser35)

  • 特异性

    Phospho-NBK (S35) Polyclonal Antibody detects endogenous levels of NBK protein only when phosphorylated at S35.

  • 基因名称

    BIK

  • 蛋白名称

    Bcl-2-interacting killer

  • 别名

    BIK;NBK;Bcl-2-interacting killer;Apoptosis inducer NBK;BIP1;BP4

  • Organism-1

    Human

  • 基因ID-1

    638

  • SwissProt-1

    Q13323

  • Organism-2

    Mouse

  • SwissProt-2

    O70337

  • 背景

    The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011],

  • 细胞定位

    Endomembrane system; Single-pass membrane protein. Mitochondrion membrane ; Single-pass membrane protein . Around the nuclear envelope, and in cytoplasmic membranes.